Outcome of carbapenem resistant Klebsiella pneumoniae bloodstream infections.

Evaluation and Identification of Carbapenem Resistant Klebsiella pneumoniae Isolated from Hospitalized Patients in Qom City, (Iran)

Background and Objectives: Klebsiella pneumonia is a facultative anaerobe bacterium from enterobacteriaceae family, which causes a wide range of diseases, such as urinary tract infections, cystitis, pneumonia, surgical wounds infections, infectious endocarditis, and diffused infections, especially in patients with HIV infection and immunosuppression. The aim of this study was to identify carbap...

Add-On Therapy with Ertapenem in Infections with Multidrug Resistant Gram-Negative Bacteria: Pediatric Experience

Optimal therapy for infections with carbapenem resistant GNB is not well established due to the weakness of data. Patients presenting with bloodstream infections caused by multidrug resistant Klebsiella pneumoniae were treated with a combination treatment. Optimal therapy for infections with carbapenem resistant Gram-negative bacteria is a serious problem in pediatric patients. We presented thr...

Removal of Carbapenem-Resistant Enterobacteriaceae (CRE) from Blood by Heparin-Functional Hemoperfusion Media

Bloodstream infections due to Carbapenem-Resistant Enterobacteriaceae (CRE) are becoming more frequent and are associated with a high mortality. At present, combination antimicrobial therapy yields the best outcomes, but treatment options are limited. Many bacteria utilize heparan sulfate to bind to human cells. We studied the ability of a biomimetic device composed of polyethylene beads with e...

Combination regimens for the treatment of carbapenem-resistant Klebsiella pneumoniae bloodstream infections

Case Report Treatment for severe infections due to carbapenem-resistant Klebsiella pneumoniae in pediatric patients: combination of fosfomycin with carbapenems

The emergence of carbapenem-resistant Klebsiella pneumoniae is considered as a significant global public health challenge, especially in pediatric patients, since the optimal treatment remains undefined. We summarize the therapeutic experience of six cases with carbapenems-resistant Klebsiella pneumoniae infection occurred in pediatric intensive care unit. Related clinical symptoms and examinat...